Potential Licensees

Pharmaceutical Companies

Given the myriad medical benefits of cannabis extracts and the enormous market size, it is no wonder that Pharmaceutical Companies are aggressively investing in the medical cannabis industry.

https://www.visualcapitalist.com/the-big-pharma-takeover-of-medical-cannabis/

However, there is no technology on the market today that can deliver cannabis extracts in vapor form to meet the strict requirements of the FDA. As was explained in the Competitive Analysis section, ingesting through the pulmonary tract is the highly preferred method for most users. A pharmaceutical company could significantly benefit from utilizing a patented FDA-approved drug delivery system to deliver patented FDA-approved drugs. Such a company could also sublicense the technology to other pharmaceutical companies that develop noncompetitive drugs.

Tobacco Companies

Tobacco companies are in the best position to appreciate the value as well as the threat of the Vapor Cartridge Technology to their future business opportunities. One major value is described in the “Science” tab: It will be the only technology that can provide the dose control, formulation control and purity assurance of inhaled botanical vapors required of an FDA-approved drug; and It defines a Vapor Cartridge manufacturing process that is highly efficient, high capacity and high quality (meeting ISO 9001:2000). A major treat is described in the “Competitive Analysis” tab. VCT vapor cartridges, once successfully commercialized, will replace flower, joints, and vape pens for those customers who choose to inhale vapors rich in cannabis extracts.

Producers of adult beverages

This is the wrong strategy. THC-infused drinks will fail. Please see the case against THC-infused drinks (below). Best to use the power of an enormous distribution channel to give customers what they already desire. They can go to their favorite well-regulated liquor store and purchase a trusted product with a credit card.

The Case against THC Infused Drinks

According to the Health and Human Services, “cannabis is the most commonly used drug among those who drink, besides tobacco.” Given the fact that alcohol and THC enhance the effect of each other, it is no surprise that they are “companion drugs”. So given that simultaneous use is prevalent among users, it raises concerns of overdose.

There are two methods for users of recreational cannabis to ingest the cannabinoids and make it bioavailable (i.e., get it into the bloodstream):

1. Inhaling cannabis vapors and ingestion by the pulmonary route

Inhaled cannabinoid vapors result in rapid onset of the influence of THC (seconds) and the effects last approximately 2 hours. Bioavailability is over 50% and can be significantly enhanced with a bronchodilator. Rapid onset allows the user to get quick feedback on the effects of the drug. By way of example let’s say that a vapor cartridge has ten doses (aka “hits”). If the user is also consuming alcohol the combined effects are quickly known since the vapor gets into the bloodstream through the lungs whereas the alcohol gets ingested through the liver. Therefore, the user can easily decide, and learn for future reference, how many doses to take and when.

 

2. Swallowing cannabinoid-infused edibles or drinks and then ingesting them through the digestive tract, which for both cannabinoids and alcohol is through the liver.

According to Ezra Pryor of the American Chemical Society’s Cannabis Chemistry Subdivision

“There really is no difference between the effects of oral dosing with cannabis, whether in an edible or drinkable form,” says Pryor. “With edibles, as with infused beverages, THC becomes 11-Hydroxy-THC after passing through the stomach and liver, rather than delta-9-THC entering directly into the blood as with smoking, which will cause a completely different effect.”

Cannabinoids that enter the digestive track are first metabolized in the liver then they enter the bloodstream. This results in a number of serious drawbacks.

  1. There is a huge loss (90%) of cannabinoids. This is due to first pass metabolism. Bioavailable is only 10%.
  2. There is at least an hour before the user feels the effects of the THC and the effects last many hours (approx. 6). This delayed gratification tempts users to take more and has led to many cases of overdose in those who ingest THC infused edibles.
  3. “Enhanced effects of THC: First, mixing alcohol with any drug (taken orally) results in that drug remaining in a person’s system longer than it normally would. This is because alcohol is metabolized first by the liver. The liver assigns priority to metabolizing alcohol despite any other substances being taken at the same time. As a general rule, the liver can metabolize about one ounce of pure alcohol per hour. This means that until the levels of alcohol in the system have been metabolized, other substances remain relatively unchanged. The THC (that is taken orally) would remain in their system, and the effects would continue to accrue until it can be metabolized properly. There is scientific evidence that this occurs.” (Reference: Alcohol.com)
  4. The likelihood of a delayed overdose, when combining alcoholic drinks with THC infused drinks, is very high. This is a safety and a liability
  5. The current customer base values the feeling of combining cannabinoids with alcohol. Their current habit is to inhale vapors (in most cases by smoking) while also drinking. Suppliers of cannabinoid (THC) infused drinks are asking customers to move to a product that is far more expensive (as measured by $/mg/ml in the bloodstream), delays the desired gratification and if taken with alcohol could lead to an unpleasant and unsafe overdose that lasts many hours. In 1989 RJ Reynolds put $325 million into a new product: smokeless cigarettes. People weren’t buying them. Four months later they were discontinued. I expect that the same fate will befall THC infused drinks.

The current, enormous, customer base uses cannabis as a companion drug to alcoholic beverages. Let them switch to a better, safer, less expensive and more convenient method without changing their behavior.

Big Cannabis Cultivators

The major issue facing legal cannabis growers is the black market.

The reason for the strength of the black market is straightforward. Black marketers are selling the same retail product (dried flower heads) at a much lower price. The technical presentation in the Science section demonstrated that the Vapor Cartridge Technology will result in a product that, even after taxation, is lower cost than the black market; and it is counterfeit-proof! And will be very convenient to purchase and use. The value of the cash crop will increase as a source for processing into a vapor cartridge.

Here are some of the larger Cannabis Cultivators.

Manufacturers of extraction & processing equipment

These companies are strategically positioned to experience substantial advantages through obtaining a license for manufacturing and selling products incorporating Vapor Cartridge Technology (VCT). Existing manufacturers of extraction and processing equipment boast a solid customer base engaged in extracting cannabis oils for the creation of retail items such as tinctures for oral consumption or oils for vaping devices. These clients would highly appreciate a cost-effective process facilitating the direct conversion of flower into retail products, specifically vapor cartridges. Additionally, the extraction equipment market is fiercely competitive, with numerous players vying for prominence. For instance, there are several companies in this crowded and competitive industry, highlighting the need for a competitive edge.

An extraction equipment manufacturer stands to gain significant financial benefits by securing an exclusive legal monopoly, achieved through patent protection, for a superior method of delivering cannabis vapors to the user’s pulmonary tract. As outlined in the “Competitive Analysis” section, VCT Vapor cartridges are poised to potentially replace vaporizers utilizing cannabis extracts as a source for generating cannabis vapors.

Root Science
Agrify
Precision Extraction Solutions
ExtractionTek Stainless
Cedar Stone
Advanced Extraction Labs
Apeks Supercritical

Savvy cannabis Entrepreneurs on the West Coast

The whole West Coast (Washington State, Oregon, California) is the perfect location to launch a new business based on the “Wine Business Model”. There are ample sources of supply, a large customer base, and friendly state governments. There are also ample technical and manufacturing capabilities to commercialize the Vapor Cartridge Technology.